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康龙化成:2024年8月28日投资者关系活动记录表附件之演示文稿(英文版)

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Stock code: 300759.SZ

Stock code: 3759.HK

2024

Interim Results

August 2024Disclaimer

The documents opinions and materials presented in this presentation (the “Document”) have been prepared by Pharmaron Beijing Co. Ltd. (康龍化成(北京)新藥技術股份有限公司) (the “Company”) for use in

presentations by the Company and does not constitute a recommendation regarding the securities of the Company. You fully understand that the Document is being made available on a confidential basis and subject to

the following provisions. The contents of this Document have not been reviewed by any regulatory authority in any jurisdiction. The distribution of this Document in certain jurisdictions may be restricted by law and the

recipients into whose possession this Document comes should inform themselves about and observe such restrictions. By accessing this Document you are agreeing (i) that you have read and agree to comply with the

contents of this notice and disclaimer and (ii) to maintain absolute confidentiality regarding the information disclosed in this Document.This Document has not been independently verified and is not intended to form the basis of any investment decision. It does not constitute an offer or invitation to sell or any solicitation of any offer to subscribe for or

purchase any securities in any jurisdiction in which the making of such offer solicitation or sale would be unlawful prior to registration or qualification under the securities laws of such jurisdiction or would not otherwise

be in compliance with the laws and regulations of such jurisdiction and nothing contained herein shall form the basis of any investment decision contract or commitment whatsoever. This Document contains no

information or material which may result in it being deemed (1) to be an advertisement invitation or document containing an advertisement or invitation falling within the meaning of section 103 of the Securities and

Futures Ordinance (Chapter 571 of the Laws of Hong Kong) (the “Securities and Futures Ordinance”) or (2) in Hong Kong to have effected an offer to the public without compliance with the laws of Hong Kong or being

able to invoke any exemption available under the laws of Hong Kong and is subject to material change without notice.The securities of the Company have not been and will not be registered under the U.S. Securities Act of 1933 as amended (the “U.S. Securities Act”) or under the laws of any state of the United States. This Document

does not constitute or form a part of any offer or solicitation to purchase or subscribe for securities in the United States and is not for distribution and may not be distributed directly or indirectly in or into the United

States (including its territories and possessions any state of the United States and the District of Columbia). The securities of the Company will not be offered or sold in the United States except pursuant to an

exemption from or in a transaction not subject to the registration requirements of the U.S. Securities Act. There will be no public offer of the Company’s securities in the United States.This Document and the information contained herein as well as information presented orally or otherwise are strictly confidential and must be treated as such. Neither the information contained in this Document nor any

copy hereof may be directly or indirectly taken or transmitted into or distributed in the United States Canada Australia Japan PRC Hong Kong or any other jurisdiction which prohibits the same except in compliance

with applicable securities laws. Any failure to comply with this restriction may constitute a violation of U.S. or other jurisdiction's securities laws. Upon request the recipient will promptly return this Document and any

other written information made available in the presentation without retaining any copies.This Document does not purport to be comprehensive or to contain all the information that a recipient may need in order to evaluate the Group. No representation warranty or undertaking express or implied is given

and so far as is permitted by law no responsibility or liability is accepted by any person (for the avoidance of doubt including but not limited to the Company and its affiliates controlling persons directors officers

partners employees agents representatives or advisers of any of the foregoing) with respect to the accuracy reliability correctness fairness or completeness of this Document or its contents. The information

communicated in this presentation contains certain statements that are or may be forward looking. These statements typically contain words such as "will" "expects" “intends” “plans to” and "anticipates" and words of

similar import. These forward-looking statements reflects the current view of the Company with respect to future events are based on a number of assumptions about the Company’s operations and factors beyond the

Company’s control and are subject to significant risks and uncertainties and accordingly actual results may differ materially from these forward-looking statements. In particular but without limitation no representation

or warranty is given as to the achievement or reasonableness of and no reliance should be placed on any assumptions projections targets estimates forecasts or any forward-looking statements contained in this

Document. Each of the Company and its affiliates controlling persons directors officers partners employees agents representatives or advisers of any of the foregoing assumes no obligation to update or otherwise

revise these forward-looking statements for new information events or circumstances that occur subsequent to such dates. None of the Company and any of its affiliates controlling persons directors officers partners

employees agents representatives or advisers of any of the foregoing shall have any liability (in negligence or otherwise) in respect of the use of or reliance upon the information contained herein by you or any person

to whom the information herein is disclosed.In furnishing this Document the Company and its affiliates undertake no obligation to provide any additional information or to update this Document or any additional information or to correct any inaccuracies which may

become apparent.

2C o n t e n t s

Performance Segment Financial Future

Overview Highlights Highlights Outlook

31234

CONTENT Performance Segment Financial Future

Overview Highlights Highlights Outlook

42Q2024 Revenue Achieved Strong QoQ Growth

RMB mm 2Q2024 1Q2024 QoQ 2Q2023 YoY

Revenue 2934 2671 9.9% 2916 0.6%

Net Profit 883 231 282.9% 438 101.6%

Non-IFRSs Adjusted Net Profit 351 339 3.7% 494 -28.8%

? 2Q2024 revenue achieved strong QoQ growth over 1Q2024 and slight YoY growth over

2Q2023

? Strong net profit growth driven by the disposal of equity interests in the Company’s minority

investment in PROTEOLOGIX which also improved the Company’s cash position

? Non-IFRSs adjusted net profit temporarily declined YoY as a result of increased labor costs

(mainly from the newly added employees in 2H2023) increased syndicated loans at the end

of 2023 and the operation of new production capacities at the end of 2023 and during the

Reporting Period

Data are rounded to the nearest million 51H2024 Financials & 2024 Outlook

RMB mm 1H2024 1H2023 YoY

Revenue 5604 5640 -0.6%

Net Profit 1113 786 41.6%

Non-IFRSs Adjusted Net Profit 690 932 -25.9%

? New POs: 1H2024 new POs YoY growth of 15%+. Modest recovery in two consecutive

quarters

? Revenue: new POs of laboratory services had gradually converted into revenue in 2Q2024.Due to different delivery cycles more POs of the CMC services will be delivered from 3Q2024

? Net Margin: expect QoQ improvement of Non-IFRSs adjusted net profit margin in 3Q2024 as

a result of increased revenue

? Guidance: maintain full-year 2024 guidance of 10%+ revenue growth

Data are rounded to the nearest million 61H2024 Business Highlights

Global Platform & Customers Rich Pipeline to Fuel Future Growth

360+ new customers 2200+ active Discovery projects: 666 drug discovery

customers including all of the TOP 20 projects increased by 2.5% YoY

global pharmas CMC projects: 16 in validation & commercial

19 in PhIII 162 in PhI/II 498 in preclinical

21 R&D & manufacturing facilities across

Clinical projects: 1112 CRO projects

China UK & US providing fully-integrated including 77 in PhIII. 1500+ SMO projects

services for SM LM & CGT CRC team covers 650+ hospitals & clinical

trial centers in 140+ cities

20342 employees including 1700+

CGT projects: 21 release testing projects

overseas employees. 18241 scientists &

including 2 commercial projects. 11 CDMO

technicians representing ~90% of total projects including 1 in PhIII 6 in PhI/II 4 in

employees preclinical

71H2024 Revenue Compositions

Segments Revenue Composition Global Customers Revenue Composition

Biologics & CGT ROW 3%

Services 4% NA Revenue Declined 0.2%

Clinical Development China

Services 15% EU Revenue Grew 10.0% 15%

CN Revenue Declined 13.2%

Laboratory North

Europe

Services 60% America

17%

65%

Small Molecule

CDMO Services

21%

China/Overseas Entities Revenue Composition Diversified Customer Base Revenue Composition

New Customers

3%

China Entities Overseas TOP 20 Pharmas TOP 20

Revenue Declined 1.3% Subsidiaries Revenue Declined 7.2% Pharmas

13%14%

Overseas Subsidiaries Other Customers

Revenue Grew 4.0% Revenue Grew 0.5%

China Entities Other Repeat

87% Customers 83%

8ESG Updates

Sustainability Diversity Equity & Inclusion ESG Ratings

The Company joined the Health The Company enhanced its DEI 2023 MSCI ESG rating of BBB

Working Group of the practice and strengthened its 2023 EcoVadis Bronze Prize

Sustainable Markets Initiative occupational health and safety

(SMI) China Council and worked management in accordance with 2024 SNSI ESG Rating of AA.together with value chain ISO 45001 Selected as one of the 2024 Top

partners of the industry to make 100 A-share Listed Companies in

concerted efforts for energy The Company also strengthened ESG Excellence and 2024 Top

saving and emission reduction the DEI management of its 20 A-share Listed Companies in

supply chain and expanded its Best Practices in Corporate

supplier network Governance (G) Dimension

91234

CONTENT Performance Segment Financial Future

Overview Highlights Highlights Outlook

10Laboratory Services

RMB mm 2Q2024 1Q2024 QoQ 2Q2023 YoY 1H2024 1H2023 YoY

Revenue 1767 1605 10.1% 1728 2.3% 3371 3380 -0.3%

GPM 44.3% 43.6% 0.7pct 45.3% -1.0pct 44.0% 44.8% -0.8pct

? QoQ improvement of laboratory chemistry services revenue since 4Q2023. Steady YoY

revenue growth of bioscience services revenue which accounted for 53%+ of the segment

revenue in 1H2024

? 1H2024 new POs increased by 10%+ YoY

? 1H2024 participated in 666 drug discovery projects a YoY increase of 2.5%

? Campus III in Ningbo began operation and increased the Company’s capacities in safety

assessment DMPK and in vivo pharmacology services. The safety assessment laboratory

received China GLP certification in July 2024

Data are rounded to the nearest million 11CMC (Small Molecule CDMO) Services

RMB mm 2Q2024 1Q2024 QoQ 2Q2023 YoY 1H2024 1H2023 YoY

Revenue 594 582 2.0% 653 -9.1% 1176 1251 -6.0%

GPM 28.3% 27.3% 1.0pct 31.7% -3.4pct 27.8% 32.2% -4.4pct

? ~78% of CMC services revenue came from the existing customers of laboratory services

? 1H2024 new POs increased by 25%+ YoY. More projects will be delivered from 3Q2024

? Commercial Manufacturing: during the Reporting Period an innovative drug the Company

produced for its customer obtained NMPA approval and became its first commercial drug

product manufacturing project. In August 2024 another product also obtained NMPA approval

and marked a new milestone for the Company’s drug product commercial manufacturing

services

? Increased costs due to certain modules in Shaoxing facility transferred from CIP into fixed

assets in 4Q2023 and increased labor costs in CN & UK

Data are rounded to the nearest million 12CMC Projects Continued to Advance to Late Stage

1H2023 1H2024

+67

Preclinical Preclinical

431498

+26

Phase I/II Phase I/II

136162

-5

Phase III Phase III

2419

-13

No. of innovative drug

Validation&Commercial projects increased YoY Validation&Commercial

2916

13Clinical Development Services

RMB mm 2Q2024 1Q2024 QoQ 2Q2023 YoY 1H2024 1H2023 YoY

Revenue 452 392 15.4% 431 4.8% 843 805 4.7%

GPM 15.4% 9.3% 6.1pct 19.6% -4.2pct 12.6% 17.0% -4.4pct

? As a result of synergies of the Company’s integrated platform and increasing customer

recognitions of Pharmaron Clinical the Company has continued to increase its number of

projects and gain market share

? 1112 clinical CRO projects including 77 PhIII clinical trials 409 PhI/II clinical trials and 626

other clinical trials

? 1500+ SMO projects. CRC team covers 650+ hospitals & clinical trial centers in 140+ cities

? GPM declined due to revenue mix of different projects and competitions in China market.

2Q2024 GPM improved QoQ as a result of increased revenue

Data are rounded to the nearest million 14Biologics & CGT Services

RMB mm 2Q2024 1Q2024 QoQ 2Q2023 YoY 1H2024 1H2023 YoY

Revenue 120 91 31.0% 105 14.3% 211 200 5.5%

GPM -25.9% -38.6% 12.7pct -5.3% -20.6pct -31.4% -8.3% -23.1pct

? Strong QoQ revenue growth driven by the delivery of an innovative bispecific antibody project

? 21 CGT analytical release testing projects from 17 customers including 2 commercial projects

and 9 clinical projects

? 12 GLP & non-GLP tox studies for CGT products either had been completed or are in

progress

? 11 gene therapy CDMO projects including 1 in PhIII 6 in PhI/II & 4 in preclinical

? The emerging segment is still in the investment stage. Increased operating costs and

depreciation of the biologics CDMO capacity in Ningbo

Data are rounded to the nearest million 151 2 3 4

CONTENT Performance Segment Financial Future

Overview Highlights Highlights Outlook

161H2024 Expenses for the Period

Selling and Distribution Expenses as % of Total Revenue Administrative Expenses as % of Total Revenue (1)

13.4%12.7%12.8%13.4%

2.1%2.2%2.2%2.2%2.2%11.3%

2021 2022 2023 1H2023 1H2024 2021 2022 2023 1H2023 1H2024

R&D Costs as % of Total Revenue Net Finance Costs as % of Total Revenue (2)

3.9%3.7%

3.2%0.7%

2.9%

0.1%0.1%0.1%

2.0%

2021 2022 2023 1H2023 1H2024

(1.2)%

2021 2022 2023 1H2023 1H2024

1. Excluding share-based compensation expenses recognized in administrative expenses 17

2. Net finance costs including interest expenses on bank borrowings and lease liabilities interest income and bank wealth management products related gains or lossesExpect to Achieve Positive Free Cash Flow in 2024

RMB mm

29502865

2754

205820932143

1501

1280

1100

950

2021 2022 2023 1H2023 1H2024

Net Operating Cash Flow CAPEX

Data are rounded to the nearest million 181H2024 Non-IFRSs Adjusted Net Profit

RMB mm 1H2024 1H2023

Net Profit 1113 786

Add:

Share-based Compensation Expenses 66 110

Convertible Bonds Related Losses / (Gains) (7) 57

Foreign Exchange Related (Gains) / Losses 5 (4)

Realized and Unrealized Gains From Equity

(531)(17)

Investments

One-off Loss Made by Pharmaron Shanghai Co. Ltd.

44-

due to the Business Close

Non-IFRSs Adjusted Net Profit 690 932

Data are rounded to the nearest million 191 2 3 4

CONTENT Performance Segment Financial Future

Overview Highlights Highlights Outlook

202024 Outlook

The pursuit of health and longevity is eternal and the long-term industry

fundamentals remain intact. Seeing early signs of customer demand recovery

Fully integrated service platforms can meet the needs of different kinds of

customers improving efficiency reducing cost and providing flexibility

Expect to deliver 10%+ revenue growth in 2024

Disclaimer: These forward-looking statements reflects the current view of the Company with respect to future events are based on a number of assumptions about

the Company’s operations and factors beyond the Company’s control and are subject to significant risks and uncertainties and accordingly actual results may differ 21

materially from these forward-looking statementsTHANK YOU

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